|
Palestou HOUSSEINI Tel: Mail: palestou.housseini@univ-artois.fr |
Palestou Housseini obtained a Bachelor's degree in Cell Biology and Physiology from the Université de Lille, before going on to complete a Master's 1 in Biology-Health and then a Master's 2 in Omics & Systems Biology at the same university. She specialized in cellular and molecular biology, with a particular interest in proteomics and targeted vectorization mechanisms. During her Master's 1 internship at the Structural and Functional Glycobiology Unit (UMR 8576 CNRS, Lille), she studied the influence of N-glycosylation on the localization and activity of isoforms of β4GalNT2, an enzyme involved in the biosynthesis of the Sda antigen in colon cancer. There, she developed skills in cell culture and protein analysis, applied to the study of membrane regulation mechanisms. During her Master's 2 internship at the OncoThAI laboratory (Inserm U1189, Lille), she explored the impact of 5-ALA-based photodynamic therapy (PDT) on the modulation of the immune system in the treatment of glioblastoma. Her work focused on tumor cell line culture, PBMC isolation and stimulation, and cytokine quantification (ELISA), contributing to a better understanding of the interactions between tumor and immune cells after PDT. In October 2025, Palestou joined the LBHE as a PhD student under the supervision of Dr. Julien Saint-Pol and Pr. Laurence Tilloy-Fenart. Her doctoral project, entitled “From prediction to application: identifying ways to optimize the transcytosis of extracellular vesicles across the BBB for the vectorization of brain-targeted compounds,” is funded by the Hauts-de-France Region. She is working to decipher the mechanisms of endocytosis and transcytosis of extracellular vesicles in order to design biological vectors targeting the brain.
