Publications

2022

Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood-Brain Barrier Model.

da Rocha GHO, Loiola RA, de Paula-Silva M, Shimizu F, Kanda T, Vieira A, Gosselet F, Farsky SHP.

Int J Mol Sci. 2022 Oct 24;23(21):12781.

PMID: 36361571

DOI: 10.3390/ijms232112781.

 

Challenges and opportunities in the use of transcriptomics characterization for human iPSC-derived BBB models.

Wellens S, Gosselet F, Culot M.

Toxicol In Vitro. 2022 Oct;84:105424.

PMID: 35760296

DOI:  10.1016/j.tiv.2022.105424

 

TNF-α and IL-1β Modulate Blood-Brain Barrier Permeability and Decrease Amyloid-β Peptide Efflux in a Human Blood-Brain Barrier Model.

Versele R, Sevin E, Gosselet F, Fenart L, Candela P.

Int J Mol Sci. 2022 Sep 6;23(18):10235.

PMID: 36142143

DOI :   10.3390/ijms231810235

 

Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells.

Moya ELJ, Lombardo SM, Vandenhaute E, Schneider M, Mysiorek C, Türeli AE, Kanda T, Shimizu F, Sano Y, Maubon N, Gosselet F, Günday-Türeli N, Dehouck MP.

Int J Pharm. 2022 Apr 30:121780.

PMID: 35504427

DOI:  10.1016/j.ijpharm.2022.121780

 

Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells.

Trouvilliez S, Cicero J, Lévêque R, Aubert L, Corbet C, Van Outryve A, Streule K, Angrand PO, Völkel P, Magnez R, Brysbaert G, Mysiorek C, Gosselet F, Bourette R, Adriaenssens E, Thuru X, Lagadec C, de Ruyck J, Orian-Rousseau V, Le Bourhis X, Toillon RA.

J Exp Clin Cancer Res. 2022 Mar 28;41(1):110.

PMID: 35346305

DOI:  10.1186/s13046-022-02314-4

 

A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.

Da Silva O, Probst N, Landry C, Hanak AS, Warnault P, Coisne C, Calas AG, Gosselet F, Courageux C, Gastellier AJ, Trancart M, Baati R, Dehouck MP, Jean L, Nachon F, Renard PY, Dias J.

J Med Chem. 2022 Mar 24;65(6):4649-4666.

PMID: 35255209

DOI:  10.1021/acs.jmedchem.1c01748

 

An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.

Nunes C, Singh P, Mazidi Z, Murphy C, Bourguignon A, Wellens S, Chandrasekaran V, Ghosh S, Zana M, Pamies D, Thomas A, Verfaillie C, Culot M, Dinnyes A, Hardy B, Wilmes A, Jennings P, Grillari R, Grillari J, Zurich MG, Exner T.

Toxicol In Vitro. 2022 Feb 16:105333.

PMID: 35182771

DOI:  10.1016/j.tiv.2022.105333